Sterile diluent

Bacteriostatic Water℞

for Injection, USP

Bacteriostatic water is sterile water with an added preservative, used to dissolve or dilute compatible injectable medications. Hospira’s 30 mL multi-dose vial contains 0.9% benzyl alcohol to help limit bacterial growth and is designed for repeated withdrawals.

  • 0.9% benzyl alcohol
  • Multi-dose vial
  • Prescription only
Presentation shown30 mL vial

Hospira / Pfizer
Multiple-dose plastic vial

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About this diluent

The difference is in the formulation.

Preparing an injectable medicine starts with the right diluent. The formulation and container matter because they affect compatibility, repeated access and what happens after the vial is opened.

The diluentSterile waterThe liquid used to prepare the medicine
The preservative0.9% benzyl alcohol9 mg/mL · Helps limit bacterial growth
Formulation of the featured 30 mL Hospira vial. [1]

Why some medicines need a diluent

A diluent is the liquid used to prepare a medication for administration. Some injectable medicines come as a powder that must be dissolved; this is called reconstitution. Others need dilution to reach the concentration specified in their prescribing instructions. Bacteriostatic water can perform either role when the medicine’s manufacturer identifies it as a compatible diluent.

The choice is specific to the medicine. Sterile water, bacteriostatic water and saline are not automatically interchangeable, and bacteriostatic water is intended for medication preparation—not injection on its own. [1]

What the preservative changes

“Bacteriostatic” refers to limiting bacterial growth. The featured 30 mL Hospira vial contains 0.9% benzyl alcohol for this purpose. The preservative does not protect against viruses or make a vial immune to contamination. Aseptic technique remains essential every time the vial is accessed.

That is a key distinction from Hospira’s preservative-free Sterile Water for Injection, which contains no antimicrobial agent and is supplied in single-dose containers. Leftover contents from a single-dose container should not be saved for another use, even for the same person. The medication’s requirements determine which formulation is appropriate. [1] [4] [5]

What “multi-dose” means for the vial

The multi-dose format permits repeated withdrawals from the same vial. The 30 mL on the label describes how much liquid the vial contains—not a medication dose or the amount to use for a particular preparation. That amount is determined by the medicine’s prescribing instructions.

Once punctured, a multi-dose vial has an opened-vial use period. CDC recommends dating it and discarding it within 28 days unless its manufacturer specifies a different period, never beyond the original expiration date. A prepared medication has separate storage and stability requirements: the diluent’s opened-vial period does not establish how long the mixed medicine can be kept. [1] [4]

Product details & packaging

The reference presentation

Manufacturer labeling for the 30 mL Hospira plastic vial. [1]

Contents
30 mL
Container
Multiple-dose plastic Fliptop vial
Preservative
Benzyl alcohol, 0.9% (9 mg/mL)
U.S. labeling

Packaging & manufacturer identifiers

Individual-vial NDC
0409-3977-01
Manufacturer pack NDC
0409-3977-03; 25 vials per pack

The vial size and the pack quantity describe different things: a pack of 25 contains 25 individual 30 mL vials. These packaging details do not establish what another seller currently offers. [2]

Other labeled presentations can differ. Hospira’s prescribing information also describes a 20 mL fill in a 30 mL glass vial with 1.1% benzyl alcohol. That is a different presentation, not 30 mL of the same formulation. [2]

Understand how the diluents differ.

Explore the formulations side by side, or take a closer look at the two water-based diluents.

How it works

The care experience we’re building.

Our planned service connects clinician evaluation, prescription review and pharmacy delivery in one clear path.

  1. Clinical evaluation

    An online clinician review of your medications and care needs.

  2. Prescription, when appropriate

    A clinician determines whether a prescription is suitable for your treatment.

  3. Pharmacy delivery

    Pharmacy fulfillment and delivery after the required clinical and prescription checks, subject to eligibility and availability.

Already have a prescription? Our planned service also includes a prescription-verification pathway.

More about our planned service

Use & handling

Important information

  • Not for injection on its own. Intravenous injection of the water alone can damage red blood cells.
  • Not for newborns. This product must not be used in neonates because of benzyl-alcohol toxicity.
  • Not for fluid replacement or spinal procedures. Its labeling excludes fluid replacement and epidural or spinal anesthesia procedures.

These are key restrictions from the manufacturer’s prescribing information. [1] Your clinician or pharmacist should confirm the diluent required for your medicine and explain its preparation and handling.

Read the full prescribing information (opens a new tab)

Common questions

Your questions, answered

Do I need a prescription?

The Hospira product shown is labeled prescription only. Your clinician should determine whether it is appropriate for your medication and individual needs. [1]

Can I use it with any injectable medicine?

No. Some medicines are incompatible with a particular diluent or with benzyl alcohol. Follow the medicine manufacturer’s instructions and ask your pharmacist if the required diluent is unclear. [1]

Does every vial contain 0.9% benzyl alcohol?

No. The concentration on this page applies to the 30 mL Hospira plastic vial. Other presentations can differ, so check the actual product label. [2]

How long can an opened vial be kept?

CDC recommends dating a multi-dose vial when first punctured and discarding it within 28 days unless its manufacturer specifies a different period. Never exceed the original expiration date. Discard it sooner if sterility is uncertain. This does not determine how long a medicine remains usable after mixing; follow that medicine’s instructions. [1] [4]

How should the vial be stored?

Hospira lists controlled room temperature storage at 20–25°C (68–77°F) for this product. Follow the actual vial’s labeling. After a medicine is mixed, its manufacturer’s instructions determine storage and how soon it must be used; the diluent’s storage conditions do not establish those requirements. [1]

Source notes

Sources & manufacturer information

  1. Pfizer Medical: Bacteriostatic Water for Injection prescribing information (opens a new tab)
  2. DailyMed: Hospira Bacteriostatic Water label and packaging (opens a new tab)
  3. Pfizer / Hospira: full product label and presentations (opens a new tab)
  4. CDC: Preventing Unsafe Injection Practices (opens a new tab)
  5. Pfizer Medical: Sterile Water for Injection prescribing information (opens a new tab)